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Coumadin is used to help prevent and treat blood clots in the legs, lungs, and those clots associated with heart-valve replacement or an irregular, rapid heartbeat called atrial fibrillation.

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Store the hospital unit-dose blister packages in the carton until contents have been used.

Painswellinghot or cold feelingskin changesor discoloration anywhere on your bodyor.

The use of vitamin K 1 reduces response to subsequent COUMADIN therapy and patients may return to a pretreatment thrombotic status following the rapid reversal of a prolonged INRResumption of COUMADIN administration reverses the effect of vitamin Kand a therapeutic INR can again be obtained by careful dosage adjustmentIf rapid re-anticoagulation is indicatedheparin may be preferable for initial therapy.

The treatment of excessive anticoagulation is based on the level of the INRthe presence or absence of bleedingand clinical circumstancesReversal of COUMADIN anticoagulation may be obtained by discontinuing COUMADIN therapy andif necessaryby administration of oral or parenteral vitamin K 1

Ask your doctor before using any medicine for painarthritisfeveror swellingThis includes aspirinibuprofenAdvilMotrinnaproxenAlevecelecoxibCelebrexdiclofenacindomethacinmeloxicamand othersThese medicines may affect blood clotting and may also increase your risk of stomach bleeding.

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another new study shows that coumadin is just as likely to cause an increase in unstable plaque and actually increase the risk for stroke.

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